Archives of neurology
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Archives of neurology · Oct 2008
Multicenter Study Comparative StudyPrevalence of vitamin d insufficiency in patients with Parkinson disease and Alzheimer disease.
A role for vitamin D deficiency in Parkinson disease (PD) has recently been proposed. ⋯ This report of 25(OH)D concentrations in a predominantly white PD cohort demonstrates a significantly higher prevalence of hypovitaminosis in PD vs both healthy controls and patients with AD. These data support a possible role of vitamin D insufficiency in PD. Further studies are needed to determine the factors contributing to these differences and elucidate the potential role of vitamin D in pathogenesis and clinical course of PD.
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Archives of neurology · Oct 2008
Multicenter Study Clinical TrialSodium oxybate for excessive daytime sleepiness in Parkinson disease: an open-label polysomnographic study.
Many patients with Parkinson disease (PD) have excessive daytime sleepiness and numerous nocturnal sleep abnormalities. ⋯ Nocturnally administered sodium oxybate improved excessive daytime sleepiness and fatigue in PD.
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Archives of neurology · Oct 2008
Predictors of outcome in warfarin-related intracerebral hemorrhage.
Intracerebral hemorrhage (ICH) associated with warfarin sodium therapy is becoming more common as the use of this medication increases in the aging population. ⋯ Lower level of consciousness at presentation and larger initial ICH volume predict poor prognosis in patients with warfarin-associated ICH. In our study population, INR at presentation was not associated with functional outcome.