Archives of neurology
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Archives of neurology · Jan 2012
Randomized Controlled Trial Clinical TrialIntranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial.
To examine the effects of intranasal insulin administration on cognition, function, cerebral glucose metabolism, and cerebrospinal fluid biomarkers in adults with amnestic mild cognitive impairment or Alzheimer disease (AD). ⋯ These results support longer trials of intranasal insulin therapy for patients with amnestic mild cognitive impairment and patients with AD. Trial Registration clinicaltrials.gov Identifier: NCT00438568.