Archives of neurology
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Archives of neurology · Feb 2012
Pattern classification of volitional functional magnetic resonance imaging responses in patients with severe brain injury.
Recent neuroimaging investigations have explored the use of mental imagery tasks as proxies for an overt motor response, in which patients are asked to imagine performing a task, such as "Imagine yourself swimming." ⋯ Pattern classification in functional magnetic resonance imaging is a promising technique for advancing the understanding of volitional brain responses in patients with severe brain injury and may serve as a powerful complement to traditional general linear model-based univariate analysis methods.
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Archives of neurology · Feb 2012
Stiff-man syndrome and variants: clinical course, treatments, and outcomes.
Little information is available about the incidence of stiff-man syndrome (SMS) (the classic form or its variants) or about long-term treatment responses and outcomes. ⋯ Recognition of classic SMS vs variants is important because appropriate therapy improves symptoms in most patients. Classification by anatomical extent and by GAD65 antibody serostatus gives important diagnostic and prognostic information.