Archives of neurology
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Archives of neurology · Sep 2011
Comparative StudyClinical characterization of a kindred with a novel 12-octapeptide repeat insertion in the prion protein gene.
To report the clinical, electroencephalographic, and neuroradiologic findings in a kindred with a novel insertion in the prion protein gene, PRNP. ⋯ This kindred has a unique combination of clinical and neuropathologic features associated with the largest base pair insertion identified to date in PRNP and underscores the need to consider familial prion disease in the differential diagnosis of a familial frontotemporal dementia-like syndrome.
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Archives of neurology · Sep 2011
Biography Historical ArticleIn memoriam: John W. “Jack” Griffin, MD.
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Archives of neurology · Aug 2011
Referring patients for deep brain stimulation: an improving practice.
Deep brain stimulation (DBS) is a recent treatment modality. Few studies have examined referral practices for DBS. ⋯ Compared with findings in prior studies, the quality of DBS referrals has improved. The increase in referral of possible future candidates and poor candidates may reflect greater confidence in the procedure.