Problemy tuberkuleza
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Problemy tuberkuleza · Jan 1991
Case Reports[Tuberculosis in young children not vaccinated with BCG].
Manifestations of tuberculosis infection were studied in 168 infants aged 3 months to 3 years of whom 32.7% had not been given BCG vaccine at birth and 67.3% received improper vaccination (the postvaccinal skin signs were absent in all patients). In 58.9% of the infants, local tuberculosis ran along with complications: dissemination into the lungs and other organs were detected in 44.4%, bronchopulmonary lesions in 42.4%, destruction of lung tissue in 18.2% and tuberculous extrapulmonary lesions in 28.3% of the infants. ⋯ Acute tuberculosis (tuberculous meningitis, miliary and progressive tuberculosis with fatal outcome) in infancy is common in 75-100% of the unvaccinated children. Hence immunoprophylaxis of tuberculosis in newborns must be developed and improved.