Akusherstvo i ginekologii͡a
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Akush Ginekol (Sofiia) · Jan 2008
Review[Application of activated recombinant factor VII (rFVIIa, NovoSeven) in neonatology].
Recombinant activated factor VII is vitamin K dependent glycoprotein, similar as the same in the human blood plasma. First has been described in application for hemophilia, where are presented inhibitors of factors VIII and IX, later was proved that it has effectiveness in hemorrhage with different etiology. ⋯ The data shows that there is low risk of side effects of the recombinant activated factor VII in neonatal period. But still has been described as a experimental treatment.
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Vasa previa are umbilical vessels which run along the fetal membranes over or near the internal cervical os. Unprotected by the umbilical cord or placenta these vessels most often originate from velamentous insertion, low-lying and/or bilobated placenta. ⋯ In this review we present two cases of prenatally diagnosed vasa previa with successful perinatal outcome. An outline of the major sonographic markers and criteria used in the ultrasound diagnosis and differential diagnosis, as well as a step-by-step algorithm of the ultrasound examination in cases with suspected vasa previa is proposed.
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Akush Ginekol (Sofiia) · Jan 2008
[Five years survival in patients with endometrioid ovarian cancer versus patients with serous ovarian cancer].
The ovarian cancer is the most malignant disease from all oncogynecological localizations. There are different scientific opinions whether the different histological types have different prognosis and survival. The aim of our research work was to evaluate if the endometrioid cancer of the ovary has a different prognosis from the serous ovarian cancer. ⋯ In patients with endometrioid and serous ovarian cancer, while taking into consideration the age, grading, stage and level of cytoreduction--there is no difference for the five years survival or the length of survival.