The primary care companion for CNS disorders
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Prim Care Companion CNS Disord · Nov 2018
Review Case ReportsHypercalcemia and Psychosis: Case Report, Review of the Literature, and Management Considerations.
The objective of this article is to help clinicians make an accurate diagnosis by considering hypercalcemia as a potential cause of psychosis. A patient case is presented, along with a review of the literature dissecting the association between calcium and psychiatric symptoms. Clinical implications and suggestions for management of hypercalcemia and psychosis in the setting of primary hyperparathyroidism are provided.
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Prim Care Companion CNS Disord · Nov 2018
Letter Case ReportsHiccups With Dose Titration of Aripiprazole.
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Prim Care Companion CNS Disord · Nov 2018
Comparative StudyA Comparison of Early, Late, and No Treatment of Intensive Care Unit Delirium With Antipsychotics: A Retrospective Cohort Study.
To investigate the effect of early versus late versus no antipsychotic administration on intensive care unit (ICU) delirium. ⋯ Antipsychotics were not associated with changes in delirium-coma-free hours or ventilator-free hours.
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Prim Care Companion CNS Disord · Feb 2018
ReviewActual Versus Expected Doses of Half Tablets Containing Prescribed Psychoactive Substances: A Systematic Review.
To assess through a systematic review of the literature if the practice of splitting tablets containing psychoactive/psychotropic medications for medical or economic reasons would result in the expected doses. ⋯ It cannot be generalized that splitting psychoactive drugs compromises dose accuracy, thus tablet splitting might still be employed in cases in which the advantages outweigh the disadvantages. It is recommended that alternatives be adopted to prevent the disadvantages related to tablet splitting.
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Prim Care Companion CNS Disord · Dec 2017
Personality Traits and Anxiety and Depressive Disorders in Patients With Medication-Overuse Headache Versus Episodic Migraine.
An episodic migraine (EM) may lead to medication-overuse headache (MOH), an abnormal behavioral pattern of noncompliance. Anxiety disorders, mood disorders, and disorders caused by psychoactive substances other than analgesics all have been reported with MOH at higher rates than with EM. The objective of this study was to evaluate the relationships between personality traits and anxiety and depressive disorders and headache type. ⋯ Reward-dependence and self-transcendence scores were significantly lower in patients with MOH than in those with EM. These results suggest that people with lower reward-dependence and self-transcendence scores may not adequately respond to prescribed medications, leading them to the frequent use of multiple drugs at higher doses. A multidisciplinary approach to management may be suggested for migraine patients, and it is reasonable to consider behavioral therapy in conjunction with pharmacotherapy to ameliorate comorbid conditions.