Indian pacing and electrophysiology journal
-
Indian Pacing Electrophysiol J · Jan 2021
ReviewHydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis.
Among many drugs that hold potential in COVID-19 pandemic, chloroquine (CQ), and its derivative hydroxychloroquine (HCQ) have generated unusual interest. With increasing usage, there has been growing concern about the prolongation of QTc interval and Torsades de Pointes (TdP) with HCQ, especially in combination with azithromycin. ⋯ The use of HCQ/CQ is associated with a high prevalence of QTc prolongation. However, it is not associated with a high risk of TdP.