Acta bio-medica : Atenei Parmensis
-
Randomized Controlled Trial Clinical Trial
Prospective randomized, double-blind, controlled trial comparing Lichtenstein's repair of inguinal hernia with polypropylene mesh versus Surgisis gold soft tissue graft: preliminary results.
Although polypropylene mesh are the preferred prosthesis materials for the tension-free hernioplasties because they handle well and become quickly integrated, having reduced the recurrence rate below 1%, some problems with their use are still to be addressed (postoperative pain, long-term discomfort, infections, intestinal obstruction and fistulization). In order to answer to these disadvantages, a new degradable and reabsorbable material, the porcine small intestinal submucosa (SIS mesh gold, Surgisis), has recently been used in humans for laparoscopic hernia repairs. Aim to our study is to evaluate the safety and efficacy of the Lichtenstein's hernioplasty using the Surgisis gold soft tissue graft, as a mesh, and to compare it with the traditional Lichtenstein procedure performed with polypropylene mesh. ⋯ Lichtenstein's hernioplasty using the Surgisis gold soft tissue graft has a promising safety and efficacy.
-
Malnutrition is a well-known risk factor significantly influencing the occurrence of postoperative infectious complications. There is consensus that nutritional support is an essential component of the multidisciplinary treatment of surgical and critically ill patients. Nutritional support of surgical patients can be carried out with different modalities, depending on the underlying disease and on the patient's general condition. ⋯ These substrates have been shown to up-regulate host immune responses, to control inflammatory responses and to improve nitrogen balance and protein synthesis after injury. A recent study reported that in patients with cancer of the gastro-intestinal tract the nutritional supplementation given only preoperatively was as effective as the combined pre- and postoperative (perioperative) approach, and it could reduce gastro-intestinal side effects. This is probably due to the effect of the immune-enhancing diet on the immune and inflammatory responses.