Oman medical journal
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Oman medical journal · Apr 2008
Use of ventilator bundle to prevent ventilator associated pneumonia.
To determine if the knowledge and awareness of "ventilator bundle" helped in the prevention of ventilator associated pneumonia and other outcome variables in the patients admitted to our AICU. ⋯ Introducing the concept of "ventilator bundle" helped us to reduce the incidence of VAP, reduce the incidence of upper gastrointestinal bleed. It reduced the mean duration of ventilation in both the medical and surgical patients who developed VAP. The effect on decreasing the length of stay was seen in the surgical patients only.
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Oman medical journal · Apr 2008
Antibiotic combination as empirical therapy for extended spectrum Beta-lactamase.
extended spectrum β-lactamase (ESBL) producing gram negative bacilli are becoming a growing problem worldwide with difficulties in designing a national formulary for empirical treatment of gram negative sepsis. ⋯ ESBLs have high resistance profile against Piperacillin/Tazobactam and Ciprofloxacin. The ESBLs from Oman have similar resistantce pattern as those reported from UK and USA. This resistance decreases when these drugs are combined with Amikacin. All ESBLs are susceptible to Carbapenems. However, carbepenam overuse can lead to emergence of carbapenems resistant gram negative bacilli and ESBLs. Combination of Amikacin plus Piperacillin/Tazobactam is a feasible empirical therapy for ESBLs.