The European journal of surgery = Acta chirurgica
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To monitor longitudinally the concentrations of cytokines in the plasma of patients with severe burns. ⋯ There are significant time-dependent changes in plasma concentrations of IL-1beta, IL-1ra, IFN-gamma and TNF-alpha after serious burns. IL-1ra concentrations may be influenced by size of the burn and the acute phase response; IL-1beta, IL-1ra and IL-8 may have a role in the host's response to infection; and IL-1beta may influence outcome.