The European journal of surgery = Acta chirurgica
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To measure the plasma catecholamine concentrations during an episode of haemorrhagic shock treated by intraosseous infusion of a small volume of hyperosmotic fluid in a standardised porcine model. ⋯ Intraosseous hyperosmotic resuscitation increases the circulatory performance and reduces the plasma catecholamine concentrations during haemorrhagic shock in pigs.
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To evaluate the plasma and urinary catecholamine concentrations after episodes of haemorrhagic shock treated by intraosseous infusion of a small volume of hyperosmotic fluid, followed by whole blood, in a standard porcine model. ⋯ The catecholamine measurements indicate that there may possibly be protective renal excretion of excess shock-induced plasma catecholamines after acute haemorrhage.
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Review Multicenter Study Comparative Study
Diagnostic scores for acute appendicitis. Abdominal Pain Study Group.
To assess the value of predictive scores in the diagnosis of acute appendicitis. ⋯ The original published data seemed to comply with our standardised criteria but evaluation of the scores on our database resulted in poor performances for all of them. Published data seem to be optimistically biased whereas our evaluation gives more realistic estimates of the routine performance in different clinical environments. Further well designed large scale trials are needed to investigate the clinical benefit of diagnostic scoring in acute appendicitis.
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Comparative Study
Excessive competence of the lower oesophageal sphincter after Nissen fundoplication: evaluation by three-dimensional computerised imaging.
To compare the competence of the lower oesophageal sphincter after Nissen fundoplication with that in a control group of healthy volunteers using a new computerized manometric device that integrates the pressure and length of the entire sphincter into one measurement, called the vector volume. ⋯ Nissen fundoplication corrects abnormal gastro-oesophageal reflux but abolishes normal physiological postprandial reflux; this is caused by the gastric fundus that encircling the intra-abdominal oesophagus, restores sphincter pressure and length, and modifies its shape.
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Randomized Controlled Trial Comparative Study Clinical Trial
Prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy. A prospective randomized study of metoclopramide and transdermal hyoscine.
To compare the antiemetic effects of metoclopramide and hyoscine in patients after laparoscopic cholecystectomy. ⋯ There was a high incidence of nausea and vomiting after laparoscopic cholecystectomy even after treatment with metoclopramide. Further measures are indicated, particularly for women.