The American journal of gastroenterology
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Am. J. Gastroenterol. · Jan 2002
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialUpper GI mucosal effects of parecoxib sodium in healthy elderly subjects.
The aim of this study was to compare the upper GI mucosal effects of i.v. parecoxib sodium with i.v. ketorolac tromethamine and placebo in healthy elderly subjects. ⋯ These results indicate that multiple dose administration of parecoxib sodium is safe and well tolerated in healthy elderly subjects, with a decreased risk of gastroduodenal mucosal injury compared with ketorolac.