The American journal of gastroenterology
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Am. J. Gastroenterol. · Jan 2005
Randomized Controlled Trial Clinical TrialA dose-ranging, phase II study of the efficacy and safety of alosetron in men with diarrhea-predominant IBS.
A randomized, double blind, placebo-controlled dose-ranging study was conducted to assess the efficacy of alosetron in men with diarrhea-predominant irritable bowel syndrome (IBS). ⋯ Alosetron 1 mg twice daily provided adequate relief of IBS pain and discomfort, and improved stool consistency in men with diarrhea-predominant IBS.