The American journal of gastroenterology
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Am. J. Gastroenterol. · Apr 2007
Meta AnalysisDiagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy.
Fecal calprotectin (FC) is a relatively new marker of intraluminal intestinal inflammation. Using meta-analytical techniques, the study aimed to evaluate the diagnostic precision of FC for inflammatory bowel disease (IBD) and colorectal cancer (CRC) in adults and children. ⋯ FC cannot be recommended as a screening test for CRC in the general population. FC appeared to offer a good diagnostic precision in distinguishing IBD from non-IBD diagnoses, with higher precision at a cutoff of 100 microg/g.
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Am. J. Gastroenterol. · Apr 2007
Comparative StudyCapsule endoscopy versus computed tomographic or standard angiography for the diagnosis of obscure gastrointestinal bleeding.
Capsule endoscopy (CE) is superior to push enteroscopy and small bowel barium radiography in detecting the source of obscure GI bleeding. We now compared whether CE has a superior diagnostic yield than CT angiography (CTA) or standard mesenteric angiography (ANGIO) in patients with obscure GI bleeding. ⋯ CE detects more lesions than CTA or standard mesenteric angiography in patients with obscure GI bleeding and has a therapeutic impact in almost half of the patients with positive findings.
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Am. J. Gastroenterol. · Apr 2007
Endoscopist administered sedation during ERCP: impact of chronic narcotic/benzodiazepine use and predictive risk of reversal agent utilization.
When administered by endoscopists conventional sedation regimens for endoscopic retrograde cholangipancreatography (ERCP) consist of intravenous (IV) benzodiazepines and opiates. As yet, standardized dosing regimens for individual patients do not exist. The aims of this study were to (a) determine sedative doses in patients with and without a history of narcotic or benzodiazepine use, (b) assess the frequency of reversal agent utilization, and (c) assess potential predictive factors for reversal agent utilization. ⋯ In a single, high volume ERCP center, endoscopist administered sedation was provided in 96% of cases. Patient age >or=80 yr, dose of meperidine, and the use of promethazine were independent risk factors for the need of reversal agents.