The American journal of gastroenterology
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Am. J. Gastroenterol. · Jun 2007
Funding source and conflict of interest disclosures by authors and editors in gastroenterology specialty journals.
Declarations of conflicts of interest have received considerable scrutiny in recent years. ⋯ Editors of gastroenterology and hepatology journals have been slow to implement guidelines for the disclosure of their own conflicts of interest. Disclosure of funding sources and conflicts of interest of authors is variable despite the presence of conflict of interest policies at most journals.
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Am. J. Gastroenterol. · Jun 2007
Ischemic-like cholangiopathy with secondary sclerosing cholangitis in critically ill patients.
Sclerosing cholangitis in critically ill patients (SC-CIP) is a newly described entity of severe biliary disease with progression to liver cirrhosis. The mechanisms leading to this form of cholangiopathy with stricture formation and complete obliteration of bile ducts are unknown. ⋯ SC-CIP is a severe and in most cases rapidly progressive complication of intensive care patients. Ischemic injury of the biliary tree with the formation of biliary casts and subsequent ongoing biliary infection due to multiresistant bacteria seem to be major pathogenic mechanisms in the development of this new entity of sclerosing cholangitis.