The American journal of gastroenterology
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Am. J. Gastroenterol. · Apr 2015
Comparative StudyInflammatory bowel disease in immigrants to Canada and their children: a population-based cohort study.
The risk of inflammatory bowel disease (IBD) contributed by the environment can be elucidated by assessing the risk in migrants from low prevalence to Western countries. The incidence of IBD in immigrants to Canada and their Canadian-born children was compared with nonimmigrants. ⋯ Younger age at arrival to Canada increased the risk of IBD in immigrants. Canadian-born children of immigrants from some regions assumed the high Canadian incidence of IBD, indicating that the underlying risk is activated with earlier life exposure to the Canadian environment in certain groups.
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Am. J. Gastroenterol. · Apr 2015
Familial risk of inflammatory bowel disease: a population-based cohort study 1977-2011.
Estimates of familial risk of inflammatory bowel diseases (IBDs), Crohn's disease (CD), and ulcerative colitis (UC) are needed for counseling of patients and could be used to target future prevention. We aimed to provide comprehensive population-based estimates of familial risk of IBD. ⋯ The risk of IBD is significantly increased in first -, second-, and third-degree relatives of IBD-affected cases, with up to 12% of all IBD cases being family cases. The risk is particularly pronounced in young individuals.
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Am. J. Gastroenterol. · Apr 2015
Emergency department burden of constipation in the United States from 2006 to 2011.
Although constipation is typically managed in an outpatient setting, there is an increasing trend in the frequency of constipation-related hospital visits. The aim of this study was to analyze trends related to chronic constipation (CC) in the United States with respect to emergency department (ED) visits, patient and hospital characteristics, and associated costs. ⋯ The frequency of and the associated costs of ED visits for constipation are significant and have increased notably from 2006 to 2011.