The American journal of gastroenterology
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Am. J. Gastroenterol. · Dec 2017
No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease.
The objective of the study was to investigate whether proton pump inhibitor (PPI) use is associated with an increased risk of clinically verified Alzheimer's disease (AD). ⋯ In conclusion, we found no clinically meaningful association between PPI use and risk of AD. The results for longer duration of cumulative use or use with higher doses did not indicate dose-response relationship.