The American journal of gastroenterology
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Am. J. Gastroenterol. · Feb 2002
The cost-effectiveness of vaccinating chronic hepatitis C patients against hepatitis A.
Although hepatitis A vaccination is recommended for persons with chronic liver disease, the cost-effectiveness of vaccinating patients with chronic hepatitis C virus has not been extensively studied. We evaluated its costs and benefits. ⋯ Hepatitis A vaccination of chronic hepatitis C patients would substantially reduce morbidity and mortality in all age groups examined. Consistent with other medical interventions for chronic hepatitis C patients, cost-effectiveness is most favorable for younger patients.
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Am. J. Gastroenterol. · Jan 2002
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialUpper GI mucosal effects of parecoxib sodium in healthy elderly subjects.
The aim of this study was to compare the upper GI mucosal effects of i.v. parecoxib sodium with i.v. ketorolac tromethamine and placebo in healthy elderly subjects. ⋯ These results indicate that multiple dose administration of parecoxib sodium is safe and well tolerated in healthy elderly subjects, with a decreased risk of gastroduodenal mucosal injury compared with ketorolac.