BMC pharmacology & toxicology
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BMC Pharmacol Toxicol · Sep 2012
ReviewLow rates of hepatotoxicity among Asian patients with paracetamol overdose: a review of 1024 cases.
The metabolism of paracetamol in Asians is thought to differ from Westerners. Detailed clinical features of paracetamol -induced hepatotoxicity among Asians remains largely unreported. ⋯ Paracetamol-induced hepatotoxicity rates in a multi-ethnic Asian population was low at 7.3%. Mortality and morbidity were non-existent despite high doses of paracetamol ingestion and delayed presentations to hospital.