Arquivos brasileiros de cardiologia
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Arq. Bras. Cardiol. · Mar 2009
ReviewSystematic review and meta-analysis of diagnostic and prognostic studies: a tutorial.
Systematic reviews with meta-analysis of studies on diagnostic tests or prognostic factors are research tools that are still being developed. The objective of the present paper is to describe the methodology of systematic review and meta-analysis of this type of studies, step by step. ⋯ References for the details of each statistical technique used were provided in the meta-analysis. We concluded that systematic reviews with meta-analysis of diagnostic tests or prognostic factors are useful in data compilation of various studies on the same subject, since they reduce biases and increase the statistical power of the primary research.
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Arq. Bras. Cardiol. · Mar 2009
Evaluation of baroreflex function in young spontaneously hypertensive rats.
The literature describes contradictory data regarding the onset of the baroreflex reduction in spontaneously hypertensive rats. ⋯ Our results showed that 13-week-old spontaneously hypertensive rats presented reduced baroreflex function when tested with phenylephrine.