Arquivos brasileiros de cardiologia
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Arq. Bras. Cardiol. · Apr 2013
Observational StudyImplementation of the myocardial infarction system of care in city of Belo Horizonte, Brazil.
The creation of an acute myocardial infarction (AMI) system of care aims to optimize the management of patients from early diagnosis to proper and timely treatment. ⋯ The establishment of the AMI system of care improved the access of the population to proper treatment, thus reducing AMI in-hospital mortality. [corrected].
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Arq. Bras. Cardiol. · Apr 2013
Detection of early sub-clinical trastuzumab-induced cardiotoxicity in breast cancer patients.
Trastuzumab (TZB) is a recombinant humanized monoclonal antibody, used for the treatment of HER2-positive breast cancer, with recognized associated-cardiotoxicity. The methods for its early sub-clinical detection are not well defined. ⋯ During the first 3 months of TZB treatment none of the pts presented overt heart failure or significant LVEF deterioration. A significant reduction in the E/e' ratio was detected, but neither the loading parameters nor LVEF changed significantly .