Minerva stomatologica
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Minerva stomatologica · Sep 2002
Randomized Controlled Trial Comparative Study Clinical TrialBurning mouth syndrome (BMS): an open trial of comparative efficacy of alpha-lipoic acid (thioctic acid) with other therapies.
Alpha-lipoic acid (ALA) is a potent antioxidant mitochondrial coenzyme, trometamol salt of thioctic acid, shown in clinical studies to be neuroprotective and in a preliminary study to have an effect on the symptomatology of Burning Mouth Syndrome (BMS). ⋯ These results suggest that double-blind randomized controlled multicenter studies of ALA are indicated.