Panminerva medica
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The availability of high-quality studies on the association between sleep-disordered breathing in children and delayed growth associated with the hormonal profile recorded before surgery and at follow-up is limited. ⋯ The current systematic review demonstrates a scarcity of high-quality studies on growth delay in children with sleep-disordered breathing. Significant catch-up growth after surgery in the short term and changes in IGF-1, IGFBP-3, ghrelin, and leptin levels has been reported in most published studies.
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Previous studies have demonstrated that EMP1 is an oncogene. In this paper, we aim to uncover the role of EMP1 in stimulating the malignant progression of osteosarcoma (OS) by the IRX2/MMP9 axis. ⋯ EMP1 is upregulated in OS tissues and closely linked to lymphatic metastasis and distant metastasis. It stimulates the malignant progression of OS through the IRX2/MMP9 axis.