Journal of the Royal Naval Medical Service
-
Randomized Controlled Trial
Molecular weight of hydroxyethyl starch molecules influences coagulation profile measured by thrombelastography.
The consensus about the ideal intravenous fluid in trauma patients remains open. However, hypertonic saline and hydroxyethyl starch (HES) seems to have advantages in terms of immuno-modulatory and haemodynamic effects. Nevertheless clotting abnormalities are frequently reported in association with the use of HES. We investigated the influence of light, medium and heavy molecular weight (MW) hydroxyethyl starch (HES) on coagulation in 29 healthy subjects. ⋯ This data indicate clear evidence of platelet activity per se or platelet interaction with the plasmatic coagulation system.
-
Historical Article
Anaesthesia in the Armed Forces--a history of the Triservice Apparatus.