Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns / [Chung-hua cheng hsing shao shang wai k'o tsa chih pien chi wei yüan hui pien chi]
-
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi · Mar 1991
[An experimental study of chemical debridement of full-thickness burn in rabbits by N-acetylcysteine].
N-acetylcysteine, a mucolytic expectorant, was used for debridement of a full-thickness burn in rabbits. The drug was applied 24h postburn and repeated once a day. ⋯ The debriding action of the drug is probably depolymerization of heat-denatured extracellular proteins (mainly denatured collagen and proteoglycans), disrupting specific linkage and lowering the molecular weight of eschar molecules. Acidity of the drug also promotes debriding process.