Dermatologica
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Case Reports
Poikiloderma-like cutaneous amyloidosis. Report of a case and review of the literature.
Cases of cutaneous amyloidosis which exhibit poikiloderma-like changes are extremely rare. There are at least two clinical forms of poikiloderma-like cutaneous amyloidosis (PCA): (1) the ordinary type, and (2) PCA syndrome. The PCA syndrome includes poikilodermatous skin manifestations whicm may appear early in life and lichenoid papules, both with cutaneous amyloid deposits, frequently associated with light sensitivity and short stature, occasionally with palmoplantar keratosis and blister formation. We carried out an examination of a 5-year-old girl who was compatible with the syndrome.
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The results obtained with low-dosage treatment with 2 mg cyproterone acetate and 0.05 mg ethinyl estradiol in 10 women with moderate to severe acne are reported. Eight of these patients showed a very good response, one a moderate response, and one showed no improvement after 3 months. In four patients the administration of antibiotics could be discontinued, and in most of the other patients the dose could be reduced. Three patients discontinued this treatment, two because of side effects and one because of lack of improvement.