Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Dec 1995
Randomized Controlled Trial Comparative Study Clinical TrialThe use of intranasal nitroglycerin to prevent pressor responses during intubation in general anesthesia--a comparison of various doses.
Intranasal nitroglycerin (NTG) was first reported to successfully prevent an increase in arterial blood pressure following laryngoscopy and tracheal intubation by Hill et al. Various different effective dosages of NTG have been reported. Grover et al. indicated 0.75 mg of intranasal NTG to be the most suitable dose. However, no definite conclusion has yet been made. This study was designed to compare the efficacy of four different dosages of intranasal NTG (0.3, 0.5, 0.75, and 1.0 mg) in preventing pressor responses to laryngoscopy and tracheal intubation during the induction of general anesthesia. ⋯ Intranasal NTG does not attenuate the pressor responses to laryngoscopy and tracheal intubation.
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Acta Anaesthesiol. Sin. · Dec 1995
ReviewClinical applications of excitatory amino acid antagonists in pain management.
Pain is an important indicator of stress particularly after surgical operation. It is not only a physical and mental suffering but also a main factor for postoperative complications. Relieving of postoperative pain is perquisite for improving outcome and shortening hospital stay. ⋯ Therefore, methods to avoid the narcotic-associated side effects are still being searched. Excitatory amino acid receptor antagonists, particularly the NMDA receptor, have been demonstrated to produce satisfactory analgesic effect under certain conditions. This article is an introductory overview of some possible applications of the excitatory amino acid receptor antagonists in future clinical pain management.
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Acta Anaesthesiol. Sin. · Dec 1995
Randomized Controlled Trial Clinical TrialOpioid in peripheral analgesia: intra-articular morphine for pain control after arthroscopic knee surgery.
Some authors reported that a small dose of intra-articular morphine (1-5 mg) injection provided a potent and long-acting analgesic effect on pain after arthroscopic knee surgery. However, many in other reports did not agree to this result. Therefore, the characteristic of the analgesic effect of intra-articular morphine is worth evaluation. In order to rule out the systemic action of intra-articular morphine, we designed a study to compare the efficacy of 3 mg intra-articular morphine with that of 3 mg intravenous morphine in providing analgesia after arthroscopic knee surgery. ⋯ Intra-articular morphine (3 mg) provided long-lasting analgesia from 6 to 36 h postoperatively and this effect was not due to systemic absorption of morphine.
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Acta Anaesthesiol. Sin. · Dec 1995
The preemptive effect of regional anesthesia on post-cesarean section pain.
The treatment of post-cesarean section (C/S) pain is very important. Since no previous report discussed the preemptive effect of regional anesthesia on post-C/S pain, the present study was undertaken to evaluate the efficacy of the preemptive effect of regional anesthesia on post-C/S pain. ⋯ We demonstrated that spinal or epidural anesthesia reduced the need of parenteral morphine postoperatively when compared with general anesthesia. We suggest that the use of regional anesthesia may provide a better preemptive effect for post-C/S pain.