Acta anaesthesiologica Sinica
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Acta Anaesthesiol. Sin. · Sep 1998
Randomized Controlled Trial Comparative Study Clinical TrialIntradermal injection of tramadol has local anesthetic effect: a comparison with lidocaine.
We observed that intravenous retention of tramadol with a pneumatic tourniquet on the arm inflated to 70 mmHg for one minute could effectively reduce the subsequent propofol injection pain. Tramadol is a central-acting analgesic. The local analgesic effect of tramadol on reducing propofol injection pain is not well known. ⋯ We concluded that intradermal injection of tramadol or lidocaine can produce local anesthetic effect.
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Acta Anaesthesiol. Sin. · Sep 1998
Randomized Controlled Trial Clinical TrialPre-anesthetic oral clonidine is effective to prevent post-spinal shivering.
Shivering is a common event during spinal anesthesia. Customarily we just treat it rather than prevent it. This study was designed to evaluate the efficacy of oral clonidine as a premedication to prevent post-spinal shivering. ⋯ Pre-anesthetic medication with oral clonidine 150 micrograms is effective to prevent post-spinal shivering in patients undergoing elective urological surgery.
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Acta Anaesthesiol. Sin. · Sep 1998
Randomized Controlled Trial Clinical TrialThe maternal and fetal effects of the addition of sufentanil to 0.5% spinal bupivacaine for cesarean delivery.
Opioid added to local anesthetic for spinal anesthesia was first introduced into clinical practice in 1979 with intrathecal morphine as a forerunner. As morphine is water soluble and has prolonged action, late respiratory depression following spinal anesthesia is not infrequent and is the most serious complication that causes our concern. Sufentanil which is more hydrophobic than morphine also with shorter duration of action and quicker onset when injected into the subarchnoid space could be more effective and a safer drug as an adjuvant to local anesthetic in spinal anesthesia. ⋯ The addition of intrathecal sufentanil to 0.5% bupivacaine for spinal anesthesia improved perioperative discomfort and significantly reduced the demand of post-operative analgesia but on the other hands, it tended to increase perioperative hypotension and cause mild pruritus.
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Acta Anaesthesiol. Sin. · Sep 1998
Randomized Controlled Trial Clinical TrialThe effect of coagulation protection with combination of epsilon aminocaproic acid and plasma saver in open-heart surgery.
Bleeding remains a major complication and a major determinant in the prognosis of open-heart surgery. Coagulopathy related to cardiopulmonary bypass (CPB) seems to be the culprit. Since homologous blood transfusion in many occasions is not only responsible for mobidity and mortality but also increases medical costs. Therefore, the application of autologous blood transfusion including components such as PRBC, FFP and platelets concentrate is inevitable and comes in its stead. To reduce the use of homologous plasma and platelets transfusion in open-heart surgery, we designed a study to utilize the combination of autologous platelet rich plasma (PRP) and epsilon aminocaproic acid (EACA) to evaluate its effects on blood loss and blood component transfusion in open-heart patients. ⋯ With Pre-CPB EACA as protection, reduction of both blood loss and blood transfusion could be realized in open-heart surgery.
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Acta Anaesthesiol. Sin. · Sep 1998
Case ReportsSuccinylcholine-induced cardiac arrest in unsuspected becker muscular dystrophy--a case report.
A five year-old boy undergoing elective tonsillectomy sustained cardiac arrest following the administration of a single dose of succinylcholine during induction of anesthesia. With a 10-minute cardiopulmonary resuscitation (CPR) during which intravenous calcium gluconate, epinephrine, and sodium bicarbonate were given and DC counter shock applied, we were successful to restore cardiac activity without neurological sequelae. The cause of cardiac arrest we speculated was hyperkalemia, possibly secondary to succinylcholine-induced rhabdomyolysis. It is suggested that succinylcholine should not be used in patients with known or suspected muscular dystrophy.