Clinical orthopaedics and related research
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Clin. Orthop. Relat. Res. · Sep 2015
Historical ArticleExtremity Injury and War: A Historical Reflection.
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Clin. Orthop. Relat. Res. · Sep 2015
Review Meta AnalysisWhat Are the Prognostic Factors for Radiographic Progression of Knee Osteoarthritis? A Meta-analysis.
A previous systematic review on prognostic factors for knee osteoarthritis (OA) progression showed associations for generalized OA and hyaluronic acid levels. Knee pain, radiographic severity, sex, quadriceps strength, knee injury, and regular sport activities were not associated. It has been a decade since the literature search of that review and many studies have been performed since then investigating prognostic factors for radiographic knee OA progression. ⋯ Baseline knee pain, presence of Heberden nodes, varus alignment, and high levels of serum markers hyaluronic acid and tumor necrosis factor-α predict knee OA progression. Sex, knee injury, and quadriceps strength, among others, did not predict knee OA progression. Large variation remains in definitions of knee OA and knee OA progression. Clinical studies should use more consistent definitions of these factors to facilitate data pooling by future meta-analyses.
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Clin. Orthop. Relat. Res. · Sep 2015
Review Comparative StudyBlast Injury in the Spine: Dynamic Response Index Is Not an Appropriate Model for Predicting Injury.
Improvised explosive devices are a common feature of recent asymmetric conflicts and there is a persistent landmine threat to military and humanitarian personnel. Assessment of injury risk to the spine in vehicles subjected to explosions was conducted using a standardized model, the Dynamic Response Index (DRI). However, the DRI was intended for evaluating aircraft ejection seats and has not been validated in blast conditions. ⋯ A new model needs to be developed to aid in the design of mine-protected vehicles for future conflicts.