Journal of tissue viability
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Dried amniotic membrane contains collagen matrix and key bioactive molecules like fibronectin, laminin, glycosaminoglycans and elastin. Fresh and cryopreserved human amniotic membrane has been widely explored as a biological dressing. However, fresh and cryopreserved amniotic membranes are not readily available or require special storage conditions. This investigation was aimed to study the functional and clinical efficacy of air-dried radiation sterilized amniotic membranes as dressing in burn wound care. ⋯ IR studies and microbial permeability test indicate no qualitative changes in the material property of dried gamma-irradiated amniotic membranes after 2 and 5 years of storage. Air-dried amniotic membrane with the advantage of storage at room temperature as well as functional efficiency is an ideal dressing for burn wound care.