Anaesthesia, critical care & pain medicine
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Anaesth Crit Care Pain Med · Feb 2020
ReviewAnaesthesia-specific checklists: A systematic review of impact.
Checklists are recognised as powerful tools to prevent avoidable errors in high-reliability organisations. In healthcare, the perioperative area has been a leading field in the development of a wide range of checklists. However, clinical literature on this subject is still sparse and heterogeneous, producing results that are sometimes conflicting. ⋯ Beyond the WHO surgical time-out, anaesthesia-specific checklists have been shown to be useful for provider handoffs, emergencies, and routine anaesthesia procedures. However, literature on anaesthesia-specific checklists is still limited and very heterogeneous. More large-scale studies are necessary to identify an ideal anaesthesia checklist and its most appropriate implementation method.
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Anaesth Crit Care Pain Med · Feb 2020
Observational StudyT regulatory cells activation and distribution are modified in critically ill patients with acute respiratory distress syndrome: A prospective single-centre observational study.
Acute respiratory distress syndrome (ARDS) is a common and fatal inflammatory condition. Whether T regulatory cells (Tregs) are beneficial or detrimental remains controversial, and longitudinal studies are lacking. Phenotyping of Tregs activation markers has been poorly reported. We aimed to evaluate quantitative and functional alterations in blood and bronchoalveolar Treg phenotype of ARDS patients. ⋯ Quantitative and functional alterations in Treg phenotype were observed in patients with ARDS. Whether rebalancing Tregs phenotype with therapeutic interventions would be beneficial deserves further investigations.
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Anaesth Crit Care Pain Med · Dec 2019
Randomized Controlled Trial Comparative StudyNorepinephrine versus phenylephrine infusion for prophylaxis against post-spinal anaesthesia hypotension during elective caesarean delivery: A randomised controlled trial.
Norepinephrine infusion is practical to use to reduce hypotension during caesarean section under spinal anaesthesia, and is non-inferior compared with phenylephrine.
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Anaesth Crit Care Pain Med · Dec 2019
Letter Randomized Controlled Trial Comparative StudyImmediate haemodynamic impact response to a mini-fluid challenge is independent of fluid type: A post-hoc analysis of a randomised double blinded controlled trial.