Voprosy onkologii
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The rate and pattern of primary postoperative cardiovascular complications were studied in 7,986 cancer patients who underwent thoracoabdominal surgery. The complication rate was 2.99%. The lethality rate in patients with complications was 10.0%. Such factors as the age over 60 years, concomitant heart pathology, surgical manipulation in thoracic cavity and mediastinum alone or in combination with preoperative radiation appeared to enhance the risk for postoperative cardiovascular complications development.
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The results of treatment of 134 cases of morphologically-verified localized Ewing's sarcoma were evaluated. A comparative analysis showed relapse-free survival to be significantly lower for radiation treatment (23%) than for its combination with various cytostatic drugs. ⋯ This was matched by 47% for adjuvant adriamycin or carminomycin and 56% for adriamycin plus cyclophosphamide and vincristine. Evaluation of long-term results of adjuvant chemotherapy showed sex, age and site of involvement to be of certain prognostic value.