Voprosy onkologii
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Although medication of malignancies made a considerable progress and the rates of apparent response grew markedly, those of survival among patients with disseminated solid tumors increased insignificantly. Metronomic therapy with cytostatics is a new modality of treatment via tumor vessels. ⋯ A pre-clinical study established decrease in size of tumors which initially showed resistance to treatment. However, further research in randomized investigation is needed in view of certain inconstinence of our data.