Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
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Zhonghua Liu Xing Bing Xue Za Zhi · Dec 2016
[Progress of research on azole resistance in Aspergillus fumigatus].
Being an important clinical fungal pathogen, Aspergillus (A.) fumigatus can cause fatal invasive fungal infections. Azoles are the first line drugs in treating various Aspergillus-caused diseases. ⋯ Currently, it has become an important public health issue. In this review, we summarize findings from literature regarding the following areas: the occurrence of azole resistance in A. fumigatus, the molecular mechanisms of resistance, contributing factors for the emergence of azole resistance, evolution of resistant strains and related control and prevention measures.