Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)
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Review Comparative Study
Organizational characteristics of solid-organ donor hospitals and nondonor hospitals.
Efforts to increase organ donation include serious attempts in hospital settings, where unrealized donation potential exists. Research on hospital donation must include understanding organizational as well as patient-specific influences on the donation process. ⋯ Among hospitals not currently producing organ donations, there is a sizable subgroup with donor potential. This area merits further attention.
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Randomized Controlled Trial Comparative Study Clinical Trial
New strategies using 'low-dose' mycophenolate mofetil to reduce acute rejection in patients following kidney transplantation.
Tacrolimus, microemulsion cyclosporine (Neoral), and mycophenolate mofetil (MMF) at 2 and 3 grams daily have demonstrated superior immunosuppressive properties in several recent clinical trials involving solid-organ transplants. An effective immunosuppression may be maintained with lower doses of MMF administered with either tacrolimus or microemulsion cyclosporine. ⋯ Both tacrolimus and microemulsion cyclosporine combined with "low-dose" MMF and corticosteroids provide effective immunosuppression and have similar adverse events in kidney transplant recipients.