Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
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Sichuan Da Xue Xue Bao Yi Xue Ban · Sep 2007
Randomized Controlled Trial[Verapamil effect and influence on postoperative epidural analgesia and cell factors TNFalpha, IL-6 and IL-2].
To evaluate the nonopioid analgesic drug effect and influence on serum cytokine and postoperative epidural analgesia. ⋯ Epidural verapamil analgesia can reduce analgesic cost, and the effective epidural analgesia can reduce the postoperative distress.
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Sichuan Da Xue Xue Bao Yi Xue Ban · Sep 2007
[Effect of decreased GSH on sensitivity of breast cancer cells to ADM].
Glutathione(GSH) maintains an optimum cellular redox potential. Elevated levels of GSH render some types of cancer cells resistant against anti-cancer drugs. The aim of this study was to determine the effect of a thiol-depleting agent, diethylmaleate (DEM), on the sensitivity of human breast cancer cells to ADM. ⋯ The depletion effect of DEM on the intracellular GSH could be enhanced by ADM and such depletion may be involved in the changes of the sensitivity of MCF/7 cells to ADM.