Fortschritte der Medizin
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Fortschritte der Medizin · Feb 1982
Randomized Controlled Trial Clinical Trial[Therapy of the orthostatic syndrome. Studies using dimepropion-HCI].
We treated 30 patients between 22 to 30 years of age, who showed static labile circulatory disturbances of blood pressure. We carried out a double blind study following a two week schedule using for treatment an "indirect" sympathomimeticum Dimepropion-HCI. Control of therapy was achieved by a testing program which consisted in measuring systolic and diastolic blood pressure as well as the pulse rate. ⋯ The amplitude was broadened, while the pulse rate went up only slightly. The level of flicker fusion rose, indicating heightened physical and mental shape. Side effects of disturbed orthostasis disappeared.