Fortschritte der Medizin
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Fortschritte der Medizin · Feb 1983
[Sublingual buprenorphine tablets: initial clinical experiences in long-term therapy of cancer pain].
Buprenorphine sublingual tablets (0.2 mg) were investigated in therapy of cancer pain. In 67 patients there was a good analgetic effect in 60%, even in those cases treated with other opiates before. The induction time was quite long (60 min.) but is no problem in chronic administration. ⋯ Typical opiate-side-effects were registered and well tolerated after some days' treatment. There was no respiratory depression. Buprenorphine sublingual tablets are certainly a good alternative in orally available opioids.