Seminars in thrombosis and hemostasis
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Semin. Thromb. Hemost. · Nov 2008
ReviewDeterminants of bleeding risk in patients on antithrombotic and antifibrinolytic drugs.
The risk of bleeding associated with antithrombotic and fibrinolytic therapy depends on factors that are specific for the drugs and the patients. In this narrative review, we describe the most important risk factors for bleeding for each class of drugs. ⋯ Knowledge of these risk factors helps to weigh the risk and benefit in the selection of therapy in individual patients. Moreover, some risk factors can be modified or avoided if they are recognized.