Journal of vascular and interventional neurology
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J Vasc Interv Neurol · Jan 2011
Earlier Hypothermia Attainment is Associated with Improved Outcomes after Cardiac Arrest.
Therapeutic hypothermia (TH, 32-34ºC) reduces mortality and improves neurologic outcomes after ventricular fibrillation cardiac arrest (CA). The relationship between time to achieve TH and outcomes remains undefined. We hypothesized that a shorter interval from CA to achieve TH would be associated with improved neurologic outcome. ⋯ Attaining TH within 6 hours of in or out-of-hospital CA was associated with a greater likelihood of a good neurological outcome at discharge. Time from CA to achieved TH should be included as a clinically important covariate in future studies of predictors of outcome after CA.