Zhonghua nei ke za zhi
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Zhonghua nei ke za zhi · May 2005
[A study on the relationship between alpha- and beta-isoform of glucocorticoid receptors and glucocorticoid-resistant idiopathic thrombocytopenia purpura].
To clarify the relationship between the expression of alpha- and beta-isoforms of glucocorticoid receptors (GR) and response to glucocorticoid in peripheral blood mononuclear cell (PBMC) of patients with idiopathic thrombocytopenia purpura (ITP). ⋯ It is shown that the excessive expression of GRbeta may serve as a novel predictor of glucocorticoid resistance in patients with ITP.