Zhonghua nei ke za zhi
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Zhonghua nei ke za zhi · Jul 2005
Randomized Controlled Trial[Beneficial neurohormonal profiles of beta-blockades in chronic left heart failure].
The aims of this study were to evaluate the effects of beta-blockers on neurohormonal factors in patients with chronic left heart failure (CHF). ⋯ The plasma level of NT-proBNP is more sensitive and accurate than the plasma level of PRA, Ang II and Ald in evaluation of severity and prognosis of CHF. beta-Blocker administration in patients with CHF decreases circulating levels of NT-proBNP and thus improves left ventricular function, but there is no significant effect on plasma level of PRA, Ang II and Ald.