Zhonghua nei ke za zhi
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Zhonghua nei ke za zhi · Apr 2013
Randomized Controlled Trial Multicenter Study[The efficacy and safety of tocilizumab combined with disease-modifying anti-rheumatoid drugs in the treatment of active rheumatoid arthritis: a multi-center, randomized, double-blinded, placebo-controlled trial].
To evaluate the efficacy and safety of human anti-interleukin-6 (IL-6) receptor antibody (tocilizumab) in combination with disease-modifying anti-rheumatoid drugs (DMARDs) for the treatment of rheumatoid arthritis (RA) patients with moderate to severe activity and inadequate response to DMARDs. ⋯ The study showed that tocilizumab combined with DMARDs was safe and effective in reducing articular and systemic symptoms in patients with an inadequate response to DMARDs.
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Zhonghua nei ke za zhi · Apr 2013
[The value of nitrogen washout/washin method in assessing alveolar recruitment volume in acute lung injury patients].
To evaluate the precision and feasibility of nitrogen washout/washin method in assessing lung recruitment of acute lung injury (ALI) patients. ⋯ Nitrogen washout/washin technique can be used to determine lung recruitment volume of ALI patients.
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Zhonghua nei ke za zhi · Apr 2013
[An analysis of clinical characteristics of septic acute kidney injury by using criteria of Kidney Disease: Improving Global Outcomes].
To evaluate the value of Kidney Disease: Improving Global Outcomes (KDIGO) criteria in investigating clinical feature and prognosis of acute kidney injury (AKI) patients with sepsis in ICU. ⋯ Septic AKI patients have a higher burden of illness, worse renal function and higher mortality. APACHEII score, SOFA score and RRT are independent risk factors to septic AKI mortality.