Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Clinical Trial
Automated single-trial measurement of amplitude and latency of laser-evoked potentials (LEPs) using multiple linear regression.
Laser stimulation of Adelta-fibre nociceptors in the skin evokes nociceptive-specific brain responses (laser-evoked potentials, LEPs). The largest vertex complex (N2-P2) is widely used to assess nociceptive pathways in physiological and clinical studies. The aim of this study was to develop an automated method to measure amplitudes and latencies of the N2 and P2 peaks on a single-trial basis. ⋯ This method is particularly desirable in several experimental conditions (e.g. drug studies, correlations with experimental variables, simultaneous EEG/fMRI and low signal-to-noise ratio data) and in clinical practice. The described multiple linear regression approach can be easily implemented for measuring evoked potentials in other sensory modalities.
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Comparative Study Clinical Trial
A comparison of subdermal wire electrodes with collodion-applied disk electrodes in long-term EEG recordings in ICU.
To compare long-term electroencephalographic (EEG) recordings of standard collodion-applied scalp disk electrodes (SDEs) with newly developed subdermal wire electrodes (SWEs) in comatose intensive care unit (ICU) patients. ⋯ This is the first controlled study that demonstrates the superiority of SWEs compared to SDEs in an ICU population.