Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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To describe the spontaneous evolution of tibial somatosensory evoked potentials (tSSEPs) after spinal cord injury (SCI) and its relation to neurological and functional parameters. ⋯ This exact description of the spontaneous improvements of neurophysiological, neurological and functional parameters after SCI is an important prerequisite in appraising the efficacy of new interventional therapies.
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To assess the pain-relieving effects of motor cortex electrical stimulation (MCS) within the central sulcus and the predictive factors retrospectively. ⋯ The present findings suggest that an intra-central sulcus is one of the favorable targets for MCS.
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Spinobulbomuscular atrophy, or Kennedy's disease (KD), is an X-linked inherited neurodegenerative disorder that clinically may "mimic" amyotrophic lateral sclerosis (ALS). Although KD is regarded as a pure lower motor neuron disorder, recent studies have reported on the presence of corticomotoneuron dysfunction in KD, similar to ALS. To clarify these discordant findings, the present study applied novel threshold tracking transcranial magnetic stimulation (TMS) techniques to gain further insights into corticomotoneuron function and thereby possible pathophysiological processes underlying neurodegeneration in KD. ⋯ The present study has established normal cortical excitability in KD, inferring a lack of significant cortical involvement in this disease.