Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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To assess the temporal relationship between skin nerve denervation and regeneration (dermal and intra-epidermal fibres, IENF) and functional changes (CO(2) laser-evoked potentials, LEPs, and quantitative sensory tests, QST) after topical cutaneous application of capsaicin. ⋯ Assessing skin biopsies by PGP9.5 immunostaining alone may miss significant diagnostic and prognostic information regarding regenerating nerve fibres, if other approaches are neglected, e.g. LEPs or GAP-43 immunostaining.
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Magnetoencephalography (MEG) is used for focus localization in presurgical evaluation of patients with focal epilepsies. In this proof-of-concept study, general anesthesia with etomidate was used to improve effectiveness of MEG-recordings. ⋯ These results could facilitate larger studies on the usefulness and safety of general anesthesia with etomidate that record and localize epileptic activity in patients with focal epilepsy by MEG.
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Previous evidence in epileptic subjects has shown that theta (about 4-7Hz) and gamma rhythms (about 40-45Hz) of hippocampus, amygdala, and neocortex were temporally synchronized during the listening of repeated words successfully remembered (Babiloni et al., 2009). Here we re-analyzed those electroencephalographic (EEG) data to test whether a parallel increase in amplitude of late positive event-related potentials takes place. ⋯ This ERP component is a promising neuromarker of successful memorization of repeated words in humans.
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Cerebral palsy (CP) is a motor disorder that causes physical disability in human development. Recent work has shown that somatosensory deficits are a serious problem for people with CP. There is however no information about the influence of age on brain correlates of tactile sensitivity. ⋯ Assessment of somatosensory functions may have implications for future neuromodulatory treatment of pain complaints and motor rehabilitation programs in children and adults with cerebral palsy.
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Rhythms on electroencephalography (EEG) are known to slow with cardiopulmonary bypass (CPB), however electroencephalographic bicoherence analysis, one of the methods to examine EEG synchronization, which is necessary for the understanding of the network regulation involved, has been poorly examined in this period. ⋯ CPB caused the EEG de-synchronous features, which are not quantified by the BIS algorithm. It has the possibility to increase the vulnerability of nociceptive perception.