Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Conditioning Pain Modulation (CPM) represents the various descending inhibitory mechanisms induced by a heterotopic noxious stimulation (previously termed DNIC). CPM-induced modulations in brain activity have not previously been investigated to visceral pain. Hence the aims were to assess the role of CPM in terms of: (1) psychophysics, (2) alterations in topography and amplitudes of evoked brain potentials and (3) modelling the brain activity. ⋯ The model provides a unique approach to study basic pain and pharmacological intervention in healthy volunteers as well as in patients with dysfunctional pain inhibition.
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The Hurst exponent (HE) is a nonlinear method measuring the smoothness of a fractal time series. In this study we applied the HE index, extracted from electroencephalographic (EEG) recordings, as a measure of anesthetic drug effects on brain activity. ⋯ The HEOLFB could be used as an index for accurately estimating the effect of anesthesia on brain activity.
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This study examined whether attention deficits in fragile X syndrome (FXS) can be traced back to abnormalities in basic information processing. ⋯ These findings demonstrate that auditory information processing in FXS males is critically impaired relative to visual information processing.