Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Evidence shows that repetitive transcranial magnetic stimulation (rTMS) changes cortical inhibition (CI) and excitability and that these changes may relate to its therapeutic effects. This study aimed to investigate the effects of differing durations or 'doses' of rTMS on cortical inhibition and excitability in healthy subjects. ⋯ Studies investigating the therapeutic effects of rTMS may benefit from extended dosing with increased number of pulses per session. CSP lengthening may be used to guide treatment response.
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Comparative Study
Comparison of bipolar versus monopolar extraoperative electrical cortical stimulation mapping in patients with focal epilepsy.
Extraoperative cortical stimulation (CS) for mapping of eloquent cortex in patients prior to epilepsy surgery is not standardized across centres. Two different techniques are in use, referred to as bipolar and monopolar CS. We compared the ability of bipolar versus monopolar CS to identify eloquent cortex and their safety profile in patients undergoing subdural EEG recordings. ⋯ Findings advocate the use of monopolar CS in a clinical setting.
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Cerebral vasomotor reactivity (VMR) and coherence of resting state electroencephalographic (EEG) rhythms are impaired in Alzheimer's disease (AD) patients. Here we tested the hypothesis that these two variables could be related. ⋯ In amnesic MCI patients, global EEG functional coupling is basically low in amplitude and does not react to hypercapnia.
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To investigate effects of symmetric and asymmetric stance and pushing movement on anticipatory and compensatory postural adjustments (APAs and CPAs). ⋯ The outcome of the study provides a basis for studying postural control in individuals with unilateral impairment while performing daily tasks involving pushing.