Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Randomized Controlled Trial
A cortical source localization analysis of resting EEG data after remifentanil infusion.
To explore changes in current source density locations after remifentanil infusion in healthy volunteers using source localization of the electroencephalography (EEG). ⋯ The approach offers the potential to be used for understanding the underlying mechanism of action of remifentanil on brain activity.
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Routine electrophysiological testing is often normal in the evaluation of painful diabetic neuropathy, as it is unable to detect dysfunction of thinly myelinated (Aδ) and unmyelinated (C) small fibers. Although cutaneous silent periods (CSP) and quantitative sudomotor axon reflex testing (QSART) respectively evaluate these fiber types in the extremities, these two tests have yet to be assessed together. ⋯ For clinically suspected SFN, it is preferable to test more than one small fiber type, as each possess different structural and functional properties and may be heterogeneously affected between patients.
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To determine if transcranial direct current stimulation (tDCS) reduces both acute pain perception and the resultant cardiovascular responses. ⋯ Application of tDCS shifts the pain perception threshold in healthy individuals but does not significantly modulate efferent cardiovascular control at rest or in response to pain.